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[KO Validated] AK2 Rabbit Polyclonal Antibody (CAB6519)

SKU:
CAB6519
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • KO Validated Antibodies 1 Anti-AK2 Antibody CAB6519KO Validated
  • KO Validated Antibodies 1 Anti-AK2 Antibody CAB6519KO Validated
  • KO Validated Antibodies 1 Anti-AK2 Antibody CAB6519KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] AK2 Rabbit Polyclonal Antibody
SKU:CAB6519
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-232 of human AK2 (NP_001616.1).
Sequence:MAPS VPAA EPEY PKGI RAVL LGPP GAGK GTQA PRLA ENFC VCHL ATGD MLRA MVAS GSEL GKKL KATM DAGK LVSD EMVV ELIE KNLE TPLC KNGF LLDG FPRT VRQA EMLD DLME KRKE KLDS VIEF SIPD SLLI RRIT GRLI HPKS GRSY HEEF NPPK EPMK DDIT GEPL IRRS DDNE KALK IRLQ AYHT QTTP LIEY YRKR GIHS AIDA SQTP DVVF ASIL AAFS KATC
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:ADK2; K2
Positive Sample:HL-60,Mouse liver,Mouse kidney,Rat liver
Conjugate:Unconjugated
Cellular Localization:Mitochondrion intermembrane space.
Calculated MW:26kDa
Observed MW:32kDa

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.

Purification Method:Affinity purification
Gene ID:204
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using [KO Validated] AK2 Rabbit pAb (CAB6519) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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