The KO Validated Annexin A1 Polyclonal Antibody (CAB1118) is a valuable tool for research involving Annexin A1, a protein known for its role in inflammation and cell signaling pathways. This antibody, produced in rabbits, is highly specific for human Annexin A1 and has been validated for use in Western blot applications.Annexin A1 is a key player in the resolution of inflammation, acting as an anti-inflammatory mediator by inhibiting leukocyte migration and promoting the clearance of apoptotic cells. Dysregulation of Annexin A1 has been implicated in various inflammatory disorders, making it a subject of interest in research on conditions such as arthritis, asthma, and cancer.
By targeting Annexin A1, researchers can study its role in immune regulation and inflammation, potentially leading to the development of novel therapeutics for inflammatory diseases. The high specificity and validated performance of the KO Validated Annexin A1 Polyclonal Antibody make it a reliable tool for investigating the function and regulation of Annexin A1 in diverse biological contexts.
Product Name:
[KO Validated] ANXA1 Rabbit Polyclonal Antibody
SKU:
CAB1118
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human ANXA1 (NP_000691.1).
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors.
Purification Method:
Affinity purification
Gene ID:
301
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts from normal (control) and ANXA1 knockout (KO) HeLa cells, using ANXA1 antibody (CAB1118) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
