[KO Validated] Beclin 1 Rabbit Polyclonal Antibody (CAB11761)
- SKU:
- CAB11761
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | [KO Validated] Beclin 1 Rabbit Polyclonal Antibody |
SKU: | CAB11761 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Beclin 1 (NP_003757.1). |
Sequence: | MEGS KTSN NSTM QVSF VCQR CSQP LKLD TSFK ILDR VTIQ ELTA PLLT TAQA KPGE TQEE ETNS GEEP FIET PRQD GVSR RFIP PARM MSTE SANS FTLI GEAS DGGT MENL SRRL KVTG DLFD IMSG QTDV DHPL CEEC TDTL LDQL DTQL NVTE NECQ NYKR CLEI LEQM NEDD SEQL QMEL KELA LEEE RLIQ ELED VEKN RKIV AENL EKVQ AEAE RLDQ EEAQ YQRE YSEF KRQQ LELD DELK SVEN QMRY AQTQ LDKL KKTN VFNA TFHI WHSG |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ATG6; VPS30; beclin1; Beclin 1 |
Positive Sample: | 293T,HeLa,Mouse lung,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum membrane, Endosome, Endosome membrane, Golgi apparatus, Mitochondrion, Mitochondrion membrane, Nucleus, Peripheral membrane protein, autophagosome, trans-Golgi network membrane. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8678 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |