The KO Validated CAPG Polyclonal Antibody (CAB7324) is a specialized research tool designed for studying the CAPG protein, which is involved in various cellular processes, including actin binding and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for Western blot applications. By binding specifically to the CAPG protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable tool for researchers studying cell biology, cancer biology, and immunology.
The CAPG protein, also known as gelsolin-like capping protein, plays a crucial role in cytoskeletal dynamics and cell motility, making it a key player in processes such as cell migration and invasion. Its involvement in these pathways highlights its importance in cancer progression and metastasis, as well as its potential as a therapeutic target for cancer treatment. Furthermore, the ability of the CAPG antibody to accurately detect and analyze this protein is essential for advancing our understanding of its role in normal cellular function and disease pathology.
Product Name:
[KO Validated] CAPG Rabbit Polyclonal Antibody
SKU:
CAB7324
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human CAPG (NP_001738.2).
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
822
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] CAPG Rabbit pAb (CAB7324) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
