null

[KO Validated] GSK3α Rabbit Monoclonal Antibody (CAB19060)

SKU:
CAB19060
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
  • KO Validated Antibodies 2 Anti-GSK3Alpha Antibody KO Validated CAB19060
  • KO Validated Antibodies 2 Anti-GSK3Alpha Antibody KO Validated CAB19060
  • KO Validated Antibodies 2 Anti-GSK3Alpha Antibody KO Validated CAB19060
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] GSK3α Rabbit Monoclonal Antibody
SKU:CAB19060
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GSK3α (P49840).
Sequence:MSGG GPSG GGPG GSGR ARTS SFAE PGGG GGGG GGGP GGSA SGPG GTGG GKAS VGAM GGGV GASS SGGG PGGS GGGG SGGP GAGT SFPP PGVK LGRD SGKV
Tested Applications:WB IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:GSK3 alpha; GSK3A; 3α
Positive Sample:HeLa,Rat lung,Mouse brain
Conjugate:Unconjugated
Cellular Localization:apical dendrite, axon, beta-catenin destruction complex, cytoplasm, cytosol, mitochondrion, nucleus, postsynapse, proximal dendrite
Calculated MW:51kDa
Observed MW:51kDa

This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.

Purification Method:Affinity purification
Gene ID:2931
Clone Number:ARC0462
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and GSK3α knockout (KO) HeLa cells, using [KO Validated] GSK3α Rabbit mAb (CAB19060) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

Related Products