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[KO Validated] GSK3α Rabbit Polyclonal Antibody (CAB18655)

SKU:
CAB18655
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
  • KO Validated Antibodies 2 Anti-GSK3Alpha Antibody CAB18655KO Validated
  • KO Validated Antibodies 2 Anti-GSK3Alpha Antibody CAB18655KO Validated
€139
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] GSK3α Rabbit Polyclonal Antibody
SKU:CAB18655
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 400-483 of human GSK3α (NP_063937.2).
Sequence:HSFF DELR CLGT QLPN NRPL PPLF NFSA GELS IQPS LNAI LIPP HLRS PAGT TTLT PSSQ ALTE TPTS SDWQ STDA TPTL TNSS
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:GSK3A; glycogen synthase kinase-3 alpha; 3α
Positive Sample:HeLa,U-251MG,Mouse brain,Rat brain
Cellular Localization:apical dendrite, axon, beta-catenin destruction complex, cytoplasm, cytosol, mitochondrion, nucleus, postsynapse, proximal dendrite
Calculated MW:51kDa
Observed MW:51kDa

This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.

Purification Method:Affinity purification
Gene ID:2931
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and GSK3α knockout (KO) HeLa cells, using [KO Validated] GSK3α Rabbit pAb (18655) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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