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[KO Validated] Cytokeratin 8 Rabbit Polyclonal Antibody (CAB1024)

SKU:
CAB1024
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • KO Validated Antibodies 1 Anti-Cytokeratin 8 Antibody CAB1024KO Validated
  • KO Validated Antibodies 1 Anti-Cytokeratin 8 Antibody CAB1024KO Validated
  • KO Validated Antibodies 1 Anti-Cytokeratin 8 Antibody CAB1024KO Validated
  • KO Validated Antibodies 1 Anti-Cytokeratin 8 Antibody CAB1024KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] Cytokeratin 8 Rabbit Polyclonal Antibody
SKU:CAB1024
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-483 of human Cytokeratin 8 (KRT8) (NP_002264.1).
Sequence:MSIR VTQK SYKV STSG PRAF SSRS YTSG PGSR ISSS SFSR VGSS NFRG GLGG GYGG ASGM GGIT AVTV NQSL LSPL VLEV DPNI QAVR TQEK EQIK TLNN KFAS FIDK VRFL EQQN KMLE TKWS LLQQ QKTA RSNM DNMF ESYI NNLR RQLE TLGQ EKLK LEAE LGNM QGLV EDFK NKYE DEIN KRTE MENE FVLI KKDV DEAY MNKV ELES RLEG LTDE INFL RQLY EEEI RELQ SQIS DTSV VLSM DNSR SLDM DSII AEVK AQYE DIAN RSRA EAES MYQI KYEE LQSL AGKH GDDL RRTK TEIS EMNR NISR LQAE IEGL KGQR ASLE AAIA DAEQ RGEL AIKD ANAK LSEL EAAL QRAK QDMA RQLR EYQE LMNV KLAL DIEI ATYR KLLE GEES RLES GMQN MSIH TKTT SGYA GGLS SAYG GLTS PGLS YSLG SSFG SGAG SSSF SRTS SSRA VVVK KIET RDGK LVSE SSDV LPK
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:2000 - 1:4000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; Cytokeratin 8 (KRT8)
Positive Sample:Mouse large intestine
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm.
Calculated MW:54kDa
Observed MW:55kDa

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Purification Method:Affinity purification
Gene ID:3856
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse large intestine, using Cytokeratin 8 (KRT8) Rabbit pAb (CAB1024) at 1:4000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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