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[KO Validated] PARK7 Rabbit Polyclonal Antibody (CAB0987)

SKU:
CAB0987
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Autophagy
  • KO Validated Antibodies 1 Anti-PARK7 Antibody CAB0987KO Validated
  • KO Validated Antibodies 1 Anti-PARK7 Antibody CAB0987KO Validated
  • KO Validated Antibodies 1 Anti-PARK7 Antibody CAB0987KO Validated
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] PARK7 Rabbit Polyclonal Antibody
SKU:CAB0987
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-189 of human DJ-1/PARK7 (NP_009193.2).
Sequence:MASK RALV ILAK GAEE METV IPVD VMRR AGIK VTVA GLAG KDPV QCSR DVVI CPDA SLED AKKE GPYD VVVL PGGN LGAQ NLSE SAAV KEIL KEQE NRKG LIAA ICAG PTAL LAHE IGFG SKVT THPL AKDK MMNG GHYT YSEN RVEK DGLI LTSR GPGT SFEF ALAI VEAL NGKE VAAQ VKAP LVLK D
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:DJ1; DJ-1; GATD2; HEL-S-67p; K7
Positive Sample:HeLa,NIH/3T3,Jurkat
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cytoplasm, Lipid-anchor, Membrane raft, Mitochondrion, Nucleus.
Calculated MW:20kDa
Observed MW:20kDa

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

Purification Method:Affinity purification
Gene ID:11315
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using DJ-1/PARK7 antibody (CAB0987) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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