The [KO Validated] FSP1/S100A4 Antibody (CAB1631) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, specifically targets human samples and is validated for use in Western blot applications.S100-A4 is of particular interest in cancer research, as it has been implicated in tumor growth, metastasis, and resistance to therapy. By using this antibody to detect and analyze S100-A4 expression in various cell types, researchers can gain insights into the mechanisms by which this protein contributes to cancer progression.
This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
[KO Validated] FSP1/S100A4 Antibody
SKU:
CAB1631
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Extracellular Exosome, Extracellular Region, Extracellular Space, Neuron Projection, Nucleus, Perinuclear Region Of Cytoplasm.
Calculated MW:
12kDa
Observed MW:
12kDa
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method
Affinity purification
Gene ID
6275
RRID
AB_2861724
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using FSP1/S100A4 Rabbit pAb (CAB1631) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
