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[KO Validated] BAF57/SMARCE1 Rabbit Polyclonal Antibody (CAB13353)

SKU:
CAB13353
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
  • KO Validated Antibodies 1 Anti-SMARCE1 Antibody CAB13353KO Validated
  • KO Validated Antibodies 1 Anti-SMARCE1 Antibody CAB13353KO Validated
  • KO Validated Antibodies 1 Anti-SMARCE1 Antibody CAB13353KO Validated
  • KO Validated Antibodies 1 Anti-SMARCE1 Antibody CAB13353KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] BAF57/SMARCE1 Rabbit Polyclonal Antibody
SKU:CAB13353
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-411 of human BAF57/BAF57/SMARCE1 (NP_003070.3).
Sequence:MSKR PSYA PPPT PAPA TQMP STPG FVGY NPYS HLAY NNYR LGGN PGTN SRVT ASSG ITIP KPPK PPDK PLMP YMRY SRKV WDQV KASN PDLK LWEI GKII GGMW RDLT DEEK QEYL NEYE AEKI EYNE SMKA YHNS PAYL AYIN AKSR AEAA LEEE SRQR QSRM EKGE PYMS IQPA EDPD DYDD GFSM KHTA TARF QRNH RLIS EILS ESVV PDVR SVVT TARM QVLK RQVQ SLMV HQRK LEAE LLQI EERH QEKK RKFL ESTD SFNN ELKR LCGL KVEV DMEK IAAE IAQA EEQA RKRQ EERE KEAA EQAE RSQS SIVP EEEQ AANK GEEK KDDE NIPM ETEE THLE ETTE SQQN GEEG TSTP EDKE SGQE GVDS MAEE GTSD SNTG SESN SATV EEPP TDPI PEDE KKE
Tested Applications:WB IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:CSS5; BAF57; E1
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:47kDa
Observed MW:50kDa

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Purification Method:Affinity purification
Gene ID:6605
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using [KO Validated] BAF57/SMARCE1 Rabbit pAb (CAB13353) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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