Description
MAPK / ERK Pathway Antibody Sampler Pack (ABSP003)
The MAPK / ERK Pathway Antibody Sampler Pack from Assay Genie brings together 8 rigorously validated antibodies covering the key nodes of this pathway in a convenient 20µL trial format. It is designed to let researchers interrogate an entire signalling axis in a single, cost-effective pack, then scale up to full-size formats for the targets that matter most to their work.
| Pack Name: | MAPK / ERK Pathway Antibody Sampler Pack |
| SKU: | ABSP003 |
| Research Area: | Cancer |
| Targets Included: | 8 |
| Format: | 8 × 20µL |
| Targets: | Raf-1, B-Raf, MEK1/2, Phospho-MEK1/2, ERK1/2, Phospho-ERK1/2, RSK, Elk-1 |
| Target | Antibody | SKU | Host | Reactivity | Applications | Size |
|---|---|---|---|---|---|---|
| Raf-1 | Anti-Raf1 Monoclonal Antibody | CAB19638-20 | Rabbit | Human, Mouse, Rat | WB ELISA | 20µL |
| B-Raf | Anti-B-Raf Antibody | CAB15033-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
| MEK1/2 | Anti-MEK2 [ARC0361] Monoclonal Antibody -Knockout Validated | CAB19078-20 | Rabbit | Human, Mouse | WB ELISA | 20µL |
| Phospho-MEK1/2 | Anti-Phospho-MEK1-T292 [ARC1566] Monoclonal Antibody | CABP1021-20 | Rabbit | Human, Mouse, Rat | WB ELISA | 20µL |
| ERK1/2 | Anti-ERK1 [ARC2591] Monoclonal Antibody | CAB19561-20 | Rabbit | Human, Mouse, Rat | WB IHC-P IF/ICC IP ELISA | 20µL |
| Phospho-ERK1/2 | Anti-Phospho-ERK1-T202 + ERK2-T185 [ARC0100] Monoclonal Antibody | CABP0485-20 | Rabbit | Human, Mouse, Rat | WB IHC-P ELISA | 20µL |
| RSK | Anti-p90Rsk/RSK1/RPS6KA1 Monoclonal Antibody | CAB4695-20 | Rabbit | Human, Mouse | WB ELISA | 20µL |
| Elk-1 | Anti-ELK1 Monoclonal Antibody | CAB19046-20 | Rabbit | Human, Mouse, Rat | WB IP ELISA | 20µL |
The RAS-RAF-MEK-ERK cascade transduces growth-factor and oncogenic signals from receptor tyrosine kinases to the nucleus. Sequential phosphorylation of RAF, MEK1/2 and ERK1/2 culminates in activation of transcription factors such as Elk-1 and p90RSK, controlling proliferation, differentiation and survival; the pathway is among the most frequently dysregulated in human cancer.
| Pack Format: | 8 antibodies, 20µL each (trial size) |
| Storage: | Store at -20°C |
| Shelf Life: | 12 months |
| Shipping: | Gel pack |
Every antibody in this sampler pack is also available individually in full 100µL size for follow-on experiments and assay scale-up.