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Mouse BMP1 Recombinant Protein (N-GST)
Key Features

Mouse BMP1 Recombinant Protein (N-GST) (GXRP00934)

SKU GXRP00934
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag N-GST
Purity >90% as determined by SDS-PAGE.
$458 - $2,412

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Description

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Mouse BMP1 Recombinant Protein (N-GST)

Mouse BMP1 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Glu615-Ser848, with an N-terminal GST tag. Predicted molecular weight: 53.33 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Bone morphogenetic protein 1 (BMP1) is a ~111 kDa protein. Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. For research use only.

Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation.

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