Description
Human BMP1 Recombinant Protein (N-GST)
Human BMP1 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Glu610-Ser843, with an N-terminal GST tag. Predicted molecular weight: 53.33 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Bone morphogenetic protein 1 is a ~111 kDa protein. Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. For research use only.
Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation.
| Product Name: | Human BMP1 Recombinant Protein (N-GST) |
| SKU: | GXRP10428 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BMP-1, BMP1, Bone morphogenetic protein 1, EC:3.4.24.19, Mammalian tolloid protein, PCOLC, PCP, Procollagen C-proteinase, mTld |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Glu610-Ser843 |
| Calculated MW: | 53.33 kDa |
| UniProt: | P13497 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
