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APC Anti-Mouse CD23 Antibody [B3B4] (AGEL1890)

Datasheet MSDS
SKU AGEL1890
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone B3B4
Conjugation APC
$139 - $372

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Description

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APC Anti-Mouse CD23 Antibody [B3B4]

The Mouse CD23 Monoclonal Antibody (APC Conjugated) B3B4 (AGEL1890) is a specialized tool for researchers studying CD23, a cell surface protein with key roles in immune regulation and allergic responses. This monoclonal antibody, derived from hybridoma cells, is specifically engineered to target CD23 in mouse samples and is conjugated with APC for flow cytometry applications. By binding specifically to CD23 on the cell surface, this antibody enables precise detection and analysis in a variety of experimental settings, making it indispensable for investigations in immunology and related fields.CD23, also known as Fc epsilon RII, is a significant player in immune responses, particularly in the context of allergic reactions and B-cell function.

Its involvement in regulating IgE production and promoting immune cell activation underscores its importance in understanding immune system dynamics. Researchers can utilize this antibody to uncover the intricate mechanisms by which CD23 influences immune processes, paving the way for insights into conditions such as allergies, autoimmune diseases, and immunodeficiencies.For scientists delving into the complexities of immune modulation and allergic responses, the Mouse CD23 Monoclonal Antibody (APC Conjugated) B3B4 (AGEL1890) offers a reliable tool to advance their research endeavors and unlock new discoveries in the realm of immunology.

Product Title:APC Anti-Mouse CD23 Antibody [B3B4]
SKU:AGEL1890
Size:25µg, 100µg
Clone No:B3B4
Synonyms:Fcer2;Fcer2a;Lymphocyte IgE receptor;Fc-epsilon-RII ;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P20693
Gene ID:14128
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD23 is a 45 kD protein also known as low affinity IgE Fc receptor, FcεRII, BLAST-2, Ly-42, or B6. It is a member of the Ig family, expressed on conventional B (but not B-1) cells and follicular dendritic cells. CD23 responds to high levels of IgE by downregulating IgE secretion.
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