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PE Anti-Mouse CD3 Antibody [17A2] (AGEL0099)

Datasheet MSDS
SKU AGEL0099
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2b
Clone 17A2
Conjugation PE
Applications FC
€25 - €72

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody (PE Conjugated, 17A2) is a valuable tool for researchers studying immune responses in mice. This antibody, with the clone number 17A2, is specifically designed to target CD3, a crucial cell surface protein found on T cells.CD3 is essential for T cell activation and function, serving as a vital component of the T cell receptor complex. The PE conjugation of this antibody allows for easy detection and analysis of CD3-expressing cells through flow cytometry or fluorescence microscopy techniques.With its high specificity and sensitivity, the Mouse CD3 Monoclonal Antibody (PE Conjugated, 17A2) is ideal for investigating T cell populations, activation status, and immune responses in experimental models.

Its reliable performance and validated application make it a valuable asset for immunology research, particularly in studies focusing on T cell biology, immunotherapy, and autoimmune diseases.Researchers can use this antibody to deepen their understanding of the intricate mechanisms underlying T cell function, immune system regulation, and the development of targeted therapies for various diseases. By targeting CD3, this antibody opens up avenues for exploring T cell-mediated immune responses and advancing our knowledge of immune system dynamics in mice.

Product Title:PE Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0099
Size:50 Tests, 100 Tests, 200 Tests
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
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