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PE/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2] (AGEL2149)

Datasheet MSDS
SKU AGEL2149
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone 17A2
Conjugation PE/Cyanine5.5
€40 - €108

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2]

The PE-Cyanine5.5 Anti-Mouse CD3 Antibody (17A2) is a valuable tool for researchers studying T cell biology and immunology. This antibody, raised in rabbits, specifically targets the CD3 antigen found on the surface of T cells. Validated for use in flow cytometry applications, it allows for the detection and analysis of CD3-expressing cells in mouse samples.CD3 is a crucial component of the T cell receptor complex, essential for T cell activation and function. By targeting CD3, researchers can gain insights into T cell activation, differentiation, and communication within the immune system.

This antibody is particularly useful for studying T cell responses in various disease contexts, including infectious diseases, autoimmune disorders, and cancer.Overall, the PE-Cyanine5.5 Anti-Mouse CD3 Antibody (17A2) offers a reliable tool for investigating T cell biology and immune responses in mouse models. Its specificity and sensitivity make it a valuable asset for research aimed at understanding and manipulating T cell function in health and disease.

Product Title:PE/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL2149
Size:50 Tests, 100 Tests, 200 Tests
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
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