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Mouse IL33 Recombinant Protein (C-His)
Key Features

Mouse IL33 Recombinant Protein (C-His) (GXRP08861)

SKU GXRP08861
Product Type Recombinant Protein
Species Mouse
Expression System E. coli
Tag C-His
$458 - $2,412

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Description

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Mouse IL33 Recombinant Protein (C-His)

Mouse IL33 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Ser109-Ile266, with a C-terminal His tag. Predicted molecular weight: 19.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Interleukin-33 is a ~29 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. For research use only.

Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury.

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