UniProt Protein Function: | VAM-1: a membrane-associated of the MAGUK family. Interacts with Lin7, which localizes to postsynaptic densities of neurons and epithelial cell-cell junctions. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 7p15 Molecular Function:protein binding |
NCBI Summary: | Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9NZW5 |
NCBI GenInfo Identifier: | 42560556 |
NCBI Gene ID: | 51678 |
NCBI Accession: | Q9NZW5.2 |
UniProt Secondary Accession: | Q9NZW5,Q9H0E1, A4D157, |
UniProt Related Accession: | Q9NZW5 |
Molecular Weight: | 61,117 Da |
NCBI Full Name: | MAGUK p55 subfamily member 6 |
NCBI Synonym Full Names: | membrane palmitoylated protein 6 |
NCBI Official Symbol: | MPP6Â Â |
NCBI Official Synonym Symbols: | VAM1; p55T; PALS2; VAM-1Â Â |
NCBI Protein Information: | MAGUK p55 subfamily member 6 |
UniProt Protein Name: | MAGUK p55 subfamily member 6 |
UniProt Synonym Protein Names: | Veli-associated MAGUK 1; VAM-1 |
Protein Family: | MAGUK p55 subfamily |
UniProt Gene Name: | MPP6Â Â |
UniProt Entry Name: | MPP6_HUMAN |