The MRGPRX1 Antibody (CAB13142) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for Western blot applications. By binding specifically to the MrgprX1 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it an ideal choice for investigations in the fields of neurobiology and dermatology.MrgprX1 is known for its role in mediating itch sensations, making it a promising target for the development of treatments for conditions such as chronic itch and pruritus.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
MRGPRX1 Antibody
SKU:
CAB13142
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GPCR, MGRG2, MRGX1, SNSR4, MRGPRX1
Positive Sample:
Mouse liver, Rat liver
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
36kDa
Observed MW:
36kDa
Enables transmembrane signaling receptor activity. Involved in cell surface receptor signaling pathway and response to chloroquine. Predicted to be located in cell surface.
Purification Method
Affinity purification
Gene ID
259249
RRID
AB_2759992
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRGPRX1 Rabbit pAb (CAB13142) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
