null

Anti-MSRB3 Antibody (CAB8005)

SKU:
CAB8005
Product Type:
Antibody
Applications:
WB
IF
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:MSRB3 Rabbit Polyclonal Antibody
Antibody SKU:CAB8005
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human MSRB3 (NP_001026849.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse lung, Mouse testis, Mouse brain, Rat lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human MSRB3 (NP_001026849.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSAF NLLH LVTK SQPV ALRA CGLP SGSC RDKK NCKV VFSQ QELR KRLT PLQY HVTQ EKGT ESAF EGEY THHK DPGI YKCV VCGT PLFK SETK FDSG SGWP SFHD VINS EAIT FTDD FSYG MHRV ETSC SQCG AHLG HIFD DGPR PTGK RYCI NSAA LSFT PADS SGTA EGGS GVAS PAQA DKAE L
Gene ID:253827
Uniprot:Q8IXL7
Cellular Location:Endoplasmic reticulum, Mitochondrion
Calculated MW:20kDa
Observed MW:25kDa
Synonyms:MSRB3, DFNB74
Background:The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.
UniProt Protein Function:Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.
NCBI Summary:The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]
UniProt Code:Q8IXL7
NCBI GenInfo Identifier:73089054
NCBI Gene ID:253827
NCBI Accession:NP_001026849.1
UniProt Secondary Accession:Q8IXL7,Q6UXS2, B4DR19, B7ZAQ0,
UniProt Related Accession:Q8IXL7
Molecular Weight:20,010 Da
NCBI Full Name:methionine-R-sulfoxide reductase B3 isoform 2
NCBI Synonym Full Names:methionine sulfoxide reductase B3
NCBI Official Symbol:MSRB3  
NCBI Official Synonym Symbols:DFNB74  
NCBI Protein Information:methionine-R-sulfoxide reductase B3
UniProt Protein Name:Methionine-R-sulfoxide reductase B3
Protein Family:Methionine-R-sulfoxide reductase
UniProt Gene Name:MSRB3  
UniProt Entry Name:MSRB3_HUMAN
Anti-MSRB3 Polyclonal Antibody (CAB8005)Western blot analysis of extracts of various cell lines, using MSRB3 antibody (CAB8005) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.

Related Products