NCR3LG1 Antibody (PACO46638)
- SKU:
- PACO46638
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | NCR3LG1 Antibody (PACO46638) |
| Antibody SKU: | PACO46638 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Natural cytotoxicity triggering receptor 3 ligand 1 protein (25-262AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: B7H6 antibody at 2 µg/ml. Lane 1: Mouse heart tissue. Lane 2: Mouse liver tissue. Lane 3: Mouse brain tissue. Lane 4: Hela whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51 kDa. Observed band size: 51, 38, 32 kDa.. |
 | Immunofluorescent analysis of HepG2 cells using PACO46638 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO46638 at dilution of 1:100. |
| Background: | Triggers NCR3-dependent natural killer cell activation. |
| Synonyms: | Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6), NCR3LG1, B7H6 |
| UniProt Protein Function: | B7-H6: Triggers NCR3-dependent natural killer cell activation. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11p15.1 Cellular Component: plasma membrane Biological Process: regulation of immune response |
| NCBI Summary: | B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011] |
| UniProt Code: | Q68D85 |
| NCBI GenInfo Identifier: | 74708829 |
| NCBI Gene ID: | 374383 |
| NCBI Accession: | Q68D85.1 |
| UniProt Secondary Accession: | Q68D85,Q7Z3M6, |
| UniProt Related Accession: | Q68D85 |
| Molecular Weight: | 50,827 Da |
| NCBI Full Name: | Natural cytotoxicity triggering receptor 3 ligand 1 |
| NCBI Synonym Full Names: | natural killer cell cytotoxicity receptor 3 ligand 1 |
| NCBI Official Symbol: | NCR3LG1Â Â |
| NCBI Official Synonym Symbols: | B7H6; B7-H6; DKFZp686O24166Â Â |
| NCBI Protein Information: | natural cytotoxicity triggering receptor 3 ligand 1 |
| UniProt Protein Name: | Natural cytotoxicity triggering receptor 3 ligand 1 |
| UniProt Synonym Protein Names: | B7 homolog 6; B7-H6 |
| Protein Family: | Natural cytotoxicity triggering receptor |
| UniProt Gene Name: | NCR3LG1Â Â |
| UniProt Entry Name: | NR3L1_HUMAN |