NRL Transcription Factor Activity Assay

SKU:
TFAB00208
€599

Description

ELISA Kit Technical Manual

NRL Transcription Factor activity assay

Product Description:The Assay Genie NRL transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates Assay Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4 °C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

NRL Transcription Factor activity assay Protein Information

UniProt Protein Function:Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B (PubMed:21981118). Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 (PubMed:17335001). Binds in a sequence-specific manner to the rhodopsin promoter (PubMed:17335001).
NCBI Summary:This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008]
UniProt Code:P54845
NCBI GenInfo Identifier:5453802
NCBI Gene ID:4901
NCBI Accession:NP_006168.1
UniProt Secondary Accession:P54845,Q53XD0, A8MX14,
UniProt Related Accession:P54845
Molecular Weight:11,276 Da
NCBI Full Name:neural retina-specific leucine zipper protein isoform 1
NCBI Synonym Full Names:neural retina leucine zipper
NCBI Official Symbol:NRL
NCBI Official Synonym Symbols:RP27; D14S46E; NRL-MAF
NCBI Protein Information:neural retina-specific leucine zipper protein
UniProt Protein Name:Neural retina-specific leucine zipper protein
Protein Family:Neural retina-specific leucine zipper protein
UniProt Gene Name:NRL
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Additional Information

Product Type:
ELISA
ELISA Type:
Transcription Factor Assay
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