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Anti-PAPD7 Antibody (CAB10017)

SKU:
CAB10017
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-PAPD7 Antibody CAB10017
  • Epigenetics and Nuclear Signaling Antibodies 1 Anti-PAPD7 Antibody CAB10017
€139 - €419
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Description

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Antibody Name:Anti-PAPD7 Antibody
Antibody SKU:CAB10017
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 303-542 of human PAPD7 (NP_008930.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:1000 IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:SH-SY5Y, A-549, SW620, HeLa, Mouse liver, Mouse brain, Mouse kidney, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 303-542 of human PAPD7 (NP_008930.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GSKA HPSP GMDS RIKI KERI ATCN GEQT QNRE PESP YGQR LTLS LSSP QLLS SGSS ASSV SSLS GSDV DSDT PPCT TPSV YQFS LQAP APLM AGLP TALP MPSG KPQP TTSR TLIM TTNN QTRF TIPP PTLG VAPV PCRQ AGVE GTAS LKAV HHMS SPAI PSAS PNPL SSPH LYHK QHNG MKLS MKGS HGHT QGGG YSSV GSGG VRPP VGNR GHHQ YNRT GWRR KKHT HTRD SLPV SLSR
Gene ID:11044
Uniprot:Q5XG87
Cellular Location:Cytoplasm, Nucleus, nucleoplasm
Calculated MW:59kDa/82kDa
Observed MW:82kDa
Synonyms:PAPD7, LAK-1, LAK1, POLK, POLS, TRF4, TRF4-1, TRF41, TUTASE5
Background:The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described.
UniProt Protein Function:POLS: DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Does not play a role in replication-dependent histone mRNA degradation. Belongs to the DNA polymerase type-B-like family.
UniProt Protein Details:

Protein type:DNA replication; Transferase; DNA repair, damage; EC 2.7.7.19

Chromosomal Location of Human Ortholog: 5p15

Cellular Component: nucleus

Molecular Function:SMC protein binding

Biological Process: response to drug; sister chromatid cohesion

NCBI Summary:The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]
UniProt Code:Q5XG87
NCBI GenInfo Identifier:586830523
NCBI Gene ID:11044
NCBI Accession:Q5XG87.3
UniProt Secondary Accession:Q5XG87,O43289, Q17RZ1, Q9Y6C1, A8K1E2, M1JCE6,
UniProt Related Accession:Q5XG87
Molecular Weight:59,874 Da
NCBI Full Name:Non-canonical poly(A) RNA polymerase PAPD7
NCBI Synonym Full Names:poly(A) RNA polymerase D7, non-canonical
NCBI Official Symbol:PAPD7  
NCBI Official Synonym Symbols:LAK1; POLK; POLS; TRF4; LAK-1; TRF41; TRF4-1; TUTASE5  
NCBI Protein Information:non-canonical poly(A) RNA polymerase PAPD7
UniProt Protein Name:Non-canonical poly(A) RNA polymerase PAPD7
UniProt Synonym Protein Names:DNA polymerase sigma; LAK-1; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal uridylyltransferase 5; TUTase 5; Topoisomerase-related function protein 4-1; TRF4-1
UniProt Gene Name:PAPD7  
UniProt Entry Name:PAPD7_HUMAN
Anti-PAPD7 Antibody (CAB10017)Western blot analysis of extracts of various cell lines, using PAPD7 antibody (CAB10017) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-PAPD7 Antibody (CAB10017)Immunohistochemistry of paraffin-embedded human placenta using PAPD7 Rabbit pAb (CAB10017) at dilution of 1:50 (40x lens).

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