[KO Validated] PDIA6 Rabbit Polyclonal Antibody (CAB18092)
- SKU:
- CAB18092
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] PDIA6 Rabbit Polyclonal Antibody |
SKU: | CAB18092 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human PDIA6 (NP_005733.1). |
Sequence: | LYSS SDDV IELT PSNF NREV IQSD SLWL VEFY APWC GHCQ RLTP EWKK AATA LKDV VKVG AVDA DKHH SLGG QYGV QGFP TIKI FGSN KNRP EDYQ GGRT GEAI VDAA LSAL RQLV KDRL GGRS GGYS SGKQ GRSD SSSK KDVI ELTD DSFD KNVL DSED VWMV EFYA PWCG HCKN LEPE WAAA ASEV KEQT KGKV KLAA VDAT VNQV LASR YGIR GFPT IKIF QKGE SPVD YDGG RTRS DIVS RALD LFSD NAPP PELL EIIN EDIA KRTC EEHQ LCVV A |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | P5; ERP5; TXNDC7; A6 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endoplasmic reticulum lumen, Melanosome. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 10130 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |