PDK4 Rabbit Polyclonal Antibody (CAB13337)
- SKU:
- CAB13337
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PDK4 Rabbit Polyclonal Antibody |
SKU: | CAB13337 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 102-411 of human PDK4 (NP_002603.1). |
Sequence: | FHEK SPDD QKAL SDFV DTLI KVRN RHHN VVPT MAQG IIEY KDAC TVDP VTNQ NLQY FLDR FYMN RIST RMLM NQHI LIFS DSQT GNPS HIGS IDPN CDVV AVVQ DAFE CSRM LCDQ YYLS SPEL KLTQ VNGK FPDQ PIHI VYVP SHLH HMLF ELFK NAMR ATVE HQEN QPSL TPIE VIVV LGKE DLTI KISD RGGG VPLR IIDR LFSY TYST APTP VMDN SRNA PLAG FGYG LPIS RLYA KYFQ GDLN LYSL SGYG TDAI IYLK ALSS ESIE KLPV FNKS AFKH YQMS SEAD DWCI PSRE PKNL AKEV AM |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PDK4 |
Positive Sample: | Mouse skeletal muscle,Rat liver,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
Purification Method: | Affinity purification |
Gene ID: | 5166 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |