Description

PE Anti-Human CD20 Antibody [BCA/B20]

The PE Anti-Human CD20 Antibody (BCA-B20) offered by AssayGenie is a potent tool for researchers investigating the CD20 molecule, a key protein found on the surface of B cells. This antibody, conjugated with phycoerythrin (PE), is specifically designed for flow cytometry applications, allowing for the precise identification and analysis of CD20-expressing cells in human samples. With its high specificity and sensitivity, this antibody enables researchers to accurately study the role of CD20 in various immune processes, making it an indispensable reagent for immunology and cancer research studies. CD20 is a well-known target in the field of oncology, particularly in the treatment of B cell malignancies like lymphoma and leukemia.

The ability to detect and quantify CD20 expression using the PE Anti-Human CD20 Antibody is vital for evaluating the efficacy of novel therapeutic strategies targeting this protein. Additionally, understanding the dynamics of CD20 expression in normal and diseased states can provide valuable insights into the pathogenesis of B cell-related disorders, paving the way for the development of more effective treatment modalities. With its reliable performance and versatility, the PE Anti-Human CD20 Antibody from AssayGenie is an essential tool for advancing research in the fields of immunology and cancer biology.

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Product Title:	PE Anti-Human CD20 Antibody [BCA/B20]
SKU:	AGEL2813
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	BCA/B20
Synonyms:	B-lymphocyte antigen CD20;MS4A1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;MS4A1;CD20;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG2a, κ
Isotype Control:	PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:	Liquid
Conjugation:	PE
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P11836
Gene ID:	931
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

PE Anti-Human CD20 Antibody [BCA/B20] (AGEL2813)

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Description