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PE/GenieFluor 594 Anti-Human CD20 Antibody [BCA/B20] (AGEL3203)

Datasheet MSDS
SKU AGEL3203
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2a, k
Clone BCA/B20
Conjugation PE/AF594
€100 - €413

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Description

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PE/GenieFluor 594 Anti-Human CD20 Antibody [BCA/B20]

The PE-GenieFluor 594 Anti-Human CD20 Antibody (BCA-B20) available on the AssayGenie platform is a powerful tool for researchers studying the CD20 cell surface antigen. This antibody, conjugated with PE-GenieFluor 594, offers high sensitivity and specificity for detecting and analyzing human CD20 in various cell types.CD20 is a well-known marker found on the surface of B cells, making it a key target for immunophenotyping and cancer research. The PE-GenieFluor 594 Anti-Human CD20 Antibody (BCA-B20) is ideal for flow cytometry applications, allowing for precise identification and quantification of CD20-expressing cells in biological samples.

By utilizing this antibody, researchers can gain valuable insights into the role of CD20 in immune responses, B cell development, and the pathogenesis of diseases such as B cell lymphomas and autoimmune disorders. With its robust performance and reliable results, the PE-GenieFluor 594 Anti-Human CD20 Antibody (BCA-B20) is a valuable asset for advancing research in immunology, oncology, and beyond.

Product Title:PE/GenieFluor 594 Anti-Human CD20 Antibody [BCA/B20]
SKU:AGEL3203
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BCA/B20
Synonyms:B-lymphocyte antigen CD20;MS4A1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;MS4A1;CD20;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
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