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PER2 Rabbit Polyclonal Antibody (CAB13168)

SKU:
CAB13168
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 3 Anti-PER2 Antibody CAB13168
  • Cell Biology Antibodies 3 Anti-PER2 Antibody CAB13168
  • Cell Biology Antibodies 3 Anti-PER2 Antibody CAB13168
  • Cell Biology Antibodies 3 Anti-PER2 Antibody CAB13168
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PER2 Rabbit Polyclonal Antibody
SKU:CAB13168
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 390-565 of human PER2 (NP_073728.1).
Sequence:GQPF DYSP IRFR ARNG EYIT LDTS WSSF INPW SRKI SFII GRHK VRVG PLNE DVFA AHPC TEEK ALHP SIQE LTEQ IHRL LLQP VPHS GSSG YGSL GSNG SHEH LMSQ TSSS DSNG HEDS RRRR AEIC KNGN KTKN RSHY SHES GEQK KKSV TEMQ TNPP AEKK AVPA MEKD SLGV
Tested Applications:WB IHC-P ChIP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 ChIP,5μg antibody for 10μg-15μg of Chromatin
Synonyms:FASPS; FASPS1; PER2
Positive Sample:293T,Mouse liver
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus, nucleolus, perinuclear region.
Calculated MW:137kDa
Observed MW:136kDa

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.

Purification Method:Affinity purification
Gene ID:8864
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using PER2 Rabbit pAb (CAB13168) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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