The Peroxiredoxin 2 (PRDX2) Monoclonal Antibody (CAB4308) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit monoclonal cells, is highly specific to Peroxiredoxin-2 and has been validated for use in Western blot applications.Peroxiredoxin-2 is a critical antioxidant enzyme that plays a key role in protecting cells from oxidative damage and maintaining cellular redox balance. Dysregulation of Peroxiredoxin-2 has been implicated in various diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Peroxiredoxin 2 (PRDX2) Monoclonal Antibody
SKU:
CAB4308
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0963
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
HeLa, K-562, SH-SY5Y, Mouse brain, Mouse heart, Rat brain, Rat spleen, Rat heart
Cellular Localization:
Cytoplasm.
Calculated MW:
22kDa
Observed MW:
22kDa
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
Purification Method
Affinity purification
Gene ID
7001
RRID
AB_2863233
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Peroxiredoxin 2 (PRDX2) (PRDX2) Rabbit mAb (CAB4308) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
