Peroxiredoxin 3 (PRDX3) Rabbit Monoclonal Antibody (CAB2398)
- SKU:
- CAB2398
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | Peroxiredoxin 3 (PRDX3) Rabbit Monoclonal Antibody |
SKU: | CAB2398 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 157-256 of human Peroxiredoxin 3 (PRDX3) (PRDX3) (P30048). |
Sequence: | NIAL LSDL TKQI SRDY GVLL EGSG LALR GLFI IDPN GVIK HLSV NDLP VGRS VEET LRLV KAFQ YVET HGEV CPAN WTPD SPTI KPSP AASK EYFQ KVNQ |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | AOP1; MER5; AOP-1; PPPCD; SP-22; HBC189; SCAR32; PRO1748; prx-III; Peroxiredoxin 3 (PRDX3) |
Positive Sample: | Hep G2,MCF7,U-87MG,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Cytoplasm, Endosome |
Calculated MW: | 28kDa |
Observed MW: | 25kDa |
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.
Purification Method: | Affinity purification |
Gene ID: | 10935 |
Clone Number: | ARC0747 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |