The Phospholipid Scramblase 1 (PLSCR1) Antibody (CAB6691) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By targeting the PLSCR1 protein, this antibody enables the detection and analysis of PLSCR1 in a variety of cell types, making it suitable for research in immunology, cancer biology, and cell signaling pathways.PLSCR1 is a multifunctional protein that plays a crucial role in various cellular functions, including the externalization of phosphatidylserine during apoptosis and the regulation of immune responses.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
Phospholipid Scramblase 1 (PLSCR1) Antibody
SKU:
CAB6691
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MMTRA1B, Phospholipid Scramblase 1 (PLSCR1)
Positive Sample:
THP-1, HT-29
Cellular Localization:
Cell Membrane, Cytoplasmic Side, Lipid-Anchor, Membrane, Nucleus, Single-Pass Type Ii Membrane Protein.
Calculated MW:
35kDa
Observed MW:
35kDa
This gene encodes a phospholipid scramblase family member. The encoded protein is involved in disruption of the asymmetrical distribution of phospholipids between the inner and outer leaflets of the plasma membrane, resulting in externalization of phosphatidylserine. This cell membrane disruption plays an important role in the blood coagulation cascade as well as macrophage clearing of apoptotic cells. The encoded protein has additionally been implicated in gene regulation and interferon-induced antiviral responses.
Purification Method
Affinity purification
Gene ID
5359
RRID
AB_2767275
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Phospholipid Scramblase 1 (PLSCR1) Rabbit pAb (CAB6691) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
