Description
POU4F1 Transcription Factor Activity Assay
The POU4F1 Transcription Factor Activity Assay Kit is a powerful tool for researchers interested in studying the activity of the POU4F1 transcription factor. This kit is designed for the accurate detection of POU4F1 transcription factor activity in various samples, including cell lysates and tissue homogenates.POU4F1, also known as Brn-3a, is a transcription factor that plays a critical role in the development and function of the nervous system. It regulates the expression of genes involved in neuronal differentiation, survival, and function, making it a key player in neurodevelopmental processes.
The POU4F1 Transcription Factor Activity Assay Kit offers high sensitivity and specificity, allowing researchers to obtain reliable and reproducible results. By studying the activity of POU4F1, researchers can gain valuable insights into the molecular mechanisms underlying neuronal development and function, as well as potential therapeutic targets for neurodegenerative disorders.Overall, the POU4F1 Transcription Factor Activity Assay Kit is an essential tool for researchers looking to advance our understanding of neurodevelopment and neurodegenerative diseases.
| Product Name: | POU4F1 Transcription Factor Activity Assay |
| Product Code: | TFAB00151 |
| Target: | POU4F1 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie POU4F1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | BRS3: Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: Xq26.3 Cellular Component: neuron projection; cell soma; plasma membrane; integral to membrane Molecular Function:bombesin receptor activity Biological Process: regulation of blood pressure; bombesin receptor signaling pathway; glucose metabolic process; adult feeding behavior |
| NCBI Summary: | This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012] |
| UniProt Code: | Q01851 |
| NCBI GenInfo Identifier: | 110347449 |
| NCBI Gene ID: | 5457 |
| NCBI Accession: | NP_006228 |
| UniProt Related Accession: | Q01851 |
| Molecular Weight: | 43kDa |
| NCBI Full Name: | POU domain, class 4, transcription factor 1 |
| NCBI Synonym Full Names: | POU class 4 homeobox 1 |
| NCBI Official Symbol: | POU4F1Â Â |
| NCBI Official Synonym Symbols: | BRN3A; RDC-1; Oct-T1; brn-3AÂ Â |
| NCBI Protein Information: | POU domain, class 4, transcription factor 1 |
| UniProt Protein Name: | Bombesin receptor subtype-3 |
| Protein Family: | Bombesin receptor |
| UniProt Gene Name: | BRS3Â Â |
| UniProt Entry Name: | BRS3_HUMAN |
