Description
Pyroptosis Antibody Sampler Pack (ABSP031)
The Pyroptosis Antibody Sampler Pack from Assay Genie brings together 7 rigorously validated antibodies covering the key nodes of this pathway in a convenient 20µL trial format. It is designed to let researchers interrogate an entire signalling axis in a single, cost-effective pack, then scale up to full-size formats for the targets that matter most to their work.
| Pack Name: | Pyroptosis Antibody Sampler Pack |
| SKU: | ABSP031 |
| Research Area: | Immunology |
| Targets Included: | 7 |
| Format: | 7 × 20µL |
| Targets: | Gasdermin D, Gasdermin E, Caspase-1, Caspase-4, NLRP3, IL-1beta, ASC/PYCARD |
| Target | Antibody | SKU | Host | Reactivity | Applications | Size |
|---|---|---|---|---|---|---|
| Gasdermin D | Anti-GSDMD (Full Length+C terminal) Antibody | CAB17308-20 | Rabbit | Human, Mouse, Rat | WB IF/ICC ELISA | 20µL |
| Gasdermin E | Anti-GSDME (Full Length+N terminal) Monoclonal Antibody | CAB25293-20 | Rabbit | Human, Mouse, Rat | WB ELISA | 20µL |
| Caspase-1 | Anti-Caspase-1 p20 [ARC60705] Monoclonal Antibody | CAB23429-20 | Rabbit | Human | WB ELISA | 20µL |
| Caspase-4 | Anti-Caspase-4 Antibody | CAB19305-20 | Rabbit | Human | WB IHC-P ELISA | 20µL |
| NLRP3 | Anti-NLRP3 Antibody | CAB12694-20 | Rabbit | Human, Mouse, Rat | WB IF/ICC ELISA | 20µL |
| IL-1beta | Anti-Human IL-1beta Detection Antibody | CBMP0064 | Rabbit | Human | Sandwich ELISA | 20µL |
| ASC/PYCARD | Anti-ASC/TMS1 Monoclonal Antibody | CAB23675-20 | Rabbit | Human, Mouse, Rat | WB ELISA | 20µL |
Pyroptosis is an inflammatory, lytic form of cell death executed by gasdermin pore formation. Inflammatory caspases (caspase-1, -4/-11) cleave gasdermin D, while caspase-3 activates gasdermin E, releasing IL-1beta and alarmins downstream of inflammasome activation.
| Pack Format: | 7 antibodies, 20µL each (trial size) |
| Storage: | Store at -20°C |
| Shelf Life: | 12 months |
| Shipping: | Gel pack |
Every antibody in this sampler pack is also available individually in full 100µL size for follow-on experiments and assay scale-up.
