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RAB13 Rabbit Polyclonal Antibody (CAB10571)

SKU:
CAB10571
Product Type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 2 Anti-RAB13 Antibody CAB10571
  • Cell Biology Antibodies 2 Anti-RAB13 Antibody CAB10571
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RAB13 Rabbit Polyclonal Antibody
SKU:CAB10571
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human RAB13 (NP_002861.1).
Sequence:MAKA YDHL FKLL LIGD SGVG KTCL IIRF AEDN FNNT YIST IGID FKIR TVDI EGKK IKLQ VWDT AGQE RFKT ITTA YYRG AMGI ILVY DITD EKSF ENIQ NWMK SIKE NASA GVER LLLG NKCD MEAK RKVQ KEQA DKLA REHG IRFF ETSA KSSM NVDE AFSS LARD ILLK SGGR RSGN GNKP PSTD LKTC DKKN TNKC SLG
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:1000 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:GIG4; RAB13
Positive Sample:HeLa,293T,LO2
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cell membrane, Cell projection, Cytoplasmic side, Cytoplasmic vesicle, Cytoplasmic vesicle membrane, Golgi apparatus, Lipid-anchor, Recycling endosome membrane, lamellipodium, secretory vesicle membrane, tight junction, trans-Golgi network membrane.
Calculated MW:23kDa
Observed MW:23kDa

This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.

Purification Method:Affinity purification
Gene ID:5872
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RAB13 Rabbit pAb (CAB10571) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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