Description
Rabbit PKM Recombinant Protein (C-His)
Rabbit PKM Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Pro531, with a C-terminal His tag. Predicted molecular weight: 59.01 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Pyruvate kinase PKM is a ~58 kDa protein. Catalyzes the final rate-limiting step of glycolysis by mediating the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. For research use only.
The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
| Product Name: | Rabbit PKM Recombinant Protein (C-His) |
| SKU: | GXRP05497 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Rabbit |
| Synonyms: | Pyruvate kinase PKM, 2.7.1.40, Pyruvate kinase muscle isozyme, Threonine-protein kinase PKM2, 2.7.11.1, Tyrosine-protein kinase PKM2, 2.7.10.2, PKM |
| Tag: | C-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Pro531 |
| Calculated MW: | 59.01 kDa |
| UniProt: | P11974 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |