Description
Rat DIO1 Recombinant Protein (N-His)
Rat DIO1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg85-Phe257, with an N-terminal His tag. Predicted molecular weight: 21.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Type I iodothyronine deiodinase is a ~29 kDa protein. Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination. For research use only.
Catalyzes the deiodination of L-thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and 3',5'-diiodothyronine (3',5'-T2) to 3'-monoiodothyronine (3'-T1) via outer-ring deiodination (ORD). Catalyzes the deiodination of T4 to 3,3',5'-triiodothyronine (rT3), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine(3-T1) and 3,3'-diiodothyronine (3,3'-T2) to 3-T1 via inner-ring deiodination (IRD). Catalyzes the deiodination of rT3 to 3,3'-T2 via ORD. Catalyzes the phenolic ring deiodinations of 3,3',5'-triiodothyronamine, 3',5'-diiodothyronamine and 3,3'-diiodothyronamine as well as tyrosyl ring deiodinations of 3,5,3'-triiodothyronamine and 3,5-diiodothyronamine.
| Product Name: | Rat DIO1 Recombinant Protein (N-His) |
| SKU: | GXRP12446 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Rat |
| Synonyms: | 5DI, DIO1, DIOI, EC:1.21.99.3, EC:1.21.99.4, ITDI1, TXDI1, Type 1 DI, Type I iodothyronine deiodinase, Type-I 5'-deiodinase |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg85-Phe257 |
| Calculated MW: | 21.85 kDa |
| UniProt: | P24389 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
