100% Quality Guarantee
PhD-Level Technical Support
Key Features

Recombinant ABCE1 Monoclonal Antibody (AGEL6353)

Datasheet MSDS
SKU AGEL6353
Product Type Antibody
Reactivity Human, Mouse
Applications WB, IF
Host Species Rabbit
Clonality Monoclonal
Clone C271047
Conjugate Unconjugated
$606 - $843

Request a formal quotation

A PDF quote with its own quote number, ready for your purchasing office to raise a PO against. Back within 4 working hours, from a PhD scientist — not an autoresponder.

  • PO-ready PDFQuote number, VAT, Incoterms
  • Volume pricing appliedDiscounts from 2 kits up
  • Valid 30 daysPrices held while you get sign-off
Anything we should know? optional

No account needed. We use your details only to prepare and send this quote. If it's urgent, say so in the box and we'll come back the same working day.
Global Shipping: 80+ Countries
White Glove Service: Available upon request
Batch Consistency: Contact Sales
Distributors: 60+ Countries
Contact Sales Quote or discount
Find Distributor 50+ countries
Technical Support PhD-level team
Live Chat Available now

Description

system_update_altDatasheetsystem_update_altMSDS

Recombinant ABCE1 Monoclonal Antibody

The Recombinant ABCE1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C271047) against ABCE1. Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway. Together with PELO and HBS1L, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes. Together with PELO and HBS1L, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs; this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.

This antibody is suitable for WB and IF applications. It has been validated by WB analysis of HeLa, Panc-1, Mouse liver and IF analysis of HeLa, NIH-3T3. The target is localized to the cytoplasm, mitochondrion.

Product Name:Recombinant ABCE1 Monoclonal Antibody
SKU:AGEL6353
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:2' 5' oligoadenylate binding protein, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, ABC, ABC 38, ABC38, ABCE, ABCE 1, ABCE1, ATP binding cassette sub family E (OABP) member 1, ATP binding cassette sub family E member 1, ATP-binding cassette sub-family E member 1, HuHP 68, HuHP68, OABP, OK/SW-cl, OK/SW-cl.40, Ribonuclease 4 inhibitor, Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L inhibitor, RLI, RLI1, RNase L inhibitor, RNASEL, RNASEL1, RNASELI, RNS 4I, RNS4I
Reactivity:Human, Mouse
Immunogen:Recombinant human ABCE1 fragment
Applications:WBIF
Clonality:Recombinant Monoclonal
Clone No:C271047
Host:Rabbit
Isotype:Rabbit IgG
Target:ABCE1
Conjugation:Unconjugated
Observed MW:45 kDa
Calculated MW:34 kDa
Recommended Dilution:WB 1:500-1000; IF 1:50
UniProt:P61221
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
View AllClose

0 Reviews

Write a Review
0
Based on 0 reviews

No reviews yet. Be the first to share your experience!

View AllClose

Related Products