The Recombinant ACE2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C221609) against ACE2. ACE2 is a carboxypeptidase that catalyses the conversion of angiotensin I to angiotensin 1-9, or of angiotensin II to the vasodilator angiotensin 1-7. ACE2 is a critical component in the renin-angiotensin system (RAS). ACE2 is predominantly expressed in vascular endothelial cells of the heart and kidney and Leydig and Sertoli cells of the testis. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of TT,?Mouse placenta and IHC analysis of Human kidney, Human renal clear cell carcinoma, Human liver (negative tissue). The target is localized to the secreted, cell membrane, cytoplasm.
