The Recombinant ANGPTL3 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C211061) against ANGPTL3. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. Has a stimulatory effect on plasma triglycerides (TG), which is achieved by suppressing plasma TG clearance via inhibition of LPL activity. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB, IHC and IF applications. It has been validated by WB analysis of Human liver, IHC analysis of Human liver, Mouse liver and IF analysis of HepG2. The target is localized to the secreted.