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Key Features

Recombinant beta-2-Microglobulin Monoclonal Antibody (AGEL6776)

Datasheet MSDS
SKU AGEL6776
Product Type Antibody
Reactivity Human, Rat
Applications WB, IHC
Host Species Rabbit
Clonality Monoclonal
Clone C721471
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant beta-2-Microglobulin Monoclonal Antibody

The Recombinant beta-2-Microglobulin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C721471) against beta-2-Microglobulin. β2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system. As an integral component of the MHC class I complex, β2-microglobulin plays a critically important role in immune system function. It has important relevance to cancer biology research; for example, research studies have shown that nearly one-third of diffuse large B cell lymphomas contain mutations that inactivate β2-microglobulin gene function, thereby allowing tumor cells to escape immune detection. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Rat samples.

This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of Raji, HeLa, HepG2, Rat kidney and IHC analysis of Human skin. The target is localized to the secreted, cell surface.

Product Name:Recombinant beta-2-Microglobulin Monoclonal Antibody
SKU:AGEL6776
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:B2M, B2MG, Beta 2 microglobin, Beta 2 microglobulin, Beta 2 microglobulin precursor, Beta chain of mhc class 1 proteins, Beta chain of MHC class I molecules, Beta-2-Microglobulin, Beta-2-microglobulin form pI, Beta-2-microglobulin form pI 5.3, CDABP, CDABP0092, HDCMA22P, IMD, IMD43, β2-Microglobulin, β2M
Reactivity:Human, Rat
Immunogen:Recombinant human beta-2-Microglobulin fragment
Applications:WBIHC
Clonality:Recombinant Monoclonal
Clone No:C721471
Host:Rabbit
Isotype:Rabbit IgG
Target:beta-2-Microglobulin
Conjugation:Unconjugated
Observed MW:14 kDa
Calculated MW:14 kDa
Recommended Dilution:WB 1:500-2000; IHC 1:500-1000
UniProt:P61769
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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