The Recombinant Bid Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C323322) against Bid. BID, also named as p22 BID, can be cleaved into p11 BID, p13 BID and p15 BID. It is pro-apoptotic molecules. The major proteolytic product p15 BID allows the release of cytochrome c. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of Hela, A549, HL-60 and IHC analysis of Human liver cancer. The target is localized to the cytoplasm, cytoplasm, mitochondrion membrane, when uncleaved, it is predominantly cytoplasmic, mitochondrion membrane, a significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively, mitochondrion membrane, Associated with the mitochondrial membrane and Mitochondrion membrane, translocates to mitochondria as an integral membrane protein.