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Key Features

Recombinant Calnexin Monoclonal Antibody (AGEL6260)

Datasheet MSDS
SKU AGEL6260
Product Type Antibody
Reactivity Human
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C310954
Conjugate Unconjugated
€409 - €559

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Description

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Recombinant Calnexin Monoclonal Antibody

The Recombinant Calnexin Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C310954) against Calnexin. This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of THP-1. The target is localized to the endoplasmic reticulum membrane, Single-pass type I membrane protein, endoplasmic reticulum, melanosome, Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232).

Product Name:Recombinant Calnexin Monoclonal Antibody
SKU:AGEL6260
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:Calnexin, CALX, CANX, CNX, FLJ26570, Histocompatibility complex class I antigen binding protein p, Histocompatibility complex class I antigen binding protein p88, IP90, Major histocompatibility complex class I antigen-binding protein p88, P90
Reactivity:Human
Immunogen:Recombinant Human Calnexin protein
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C310954
Host:Rabbit
Isotype:Rabbit IgG
Target:Calnexin
Conjugation:Unconjugated
Observed MW:90 kDa
Calculated MW:68 kDa
Recommended Dilution:IHC 1:2000-10000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:P27824
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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