The Recombinant CD146/MCAM Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110177) against MCAM. Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF and FC applications. It has been validated by WB analysis of HUVEC, Mouse lung, Rat lung and IF analysis of HeLa.
WB 1:1000; IHC-P 1:200-500; ICC/IF 1:100-200; FC 1:20-100
UniProt:
P43121
Purification:
Affinity purification
Concentration:
1 mg/mL
Buffer:
0.2 µm filtered solution in PBS
Storage:
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
