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Recombinant Cdk9 Monoclonal Antibody (AGEL6205)

Datasheet MSDS
SKU AGEL6205
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110899
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant Cdk9 Monoclonal Antibody

The Recombinant Cdk9 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110899) against Cdk9. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by IHC analysis of Human pancreas. The target is localized to the Nucleus. Cytoplasm, nucleus, PML body. Accumulates on chromatin in response to replication stress. Complexed with CCNT1 in nuclear speckles, but uncomplexed form in the cytoplasm, The translocation from nucleus to cytoplasm is XPO1/CRM1-dependent. Associates with PML body when acetylated.

Product Name:Recombinant Cdk9 Monoclonal Antibody
SKU:AGEL6205
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:C-2k, CDC2L, CDC2L4, CDK, CDK9, CTK, CTK1, PITALRE, TAK
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human Cdk9 protein
Applications:WBIHCIFIPELISA
Clonality:Recombinant Monoclonal
Clone No:C110899
Host:Rabbit
Isotype:Rabbit IgG
Target:Cdk9
Conjugation:Unconjugated
Recommended Dilution:IHC 1:200-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:P50750
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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