The Recombinant CDKN2A/p14ARF Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C370699) against CDKN2A/p14ARF. CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IF, IP and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the nuclear.
Product Name:
Recombinant CDKN2A/p14ARF Monoclonal Antibody
SKU:
AGEL6008
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
CDKN, CDKN2, CDKN2A, MLM, p14ARF
Reactivity:
Human
Immunogen:
Recombinant Human CDKN2A/p14ARF protein
Applications:
WBIFIPELISA
Clonality:
Recombinant Monoclonal
Clone No:
C370699
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CDKN2A/p14ARF
Conjugation:
Unconjugated
Observed MW:
16 kDa
Calculated MW:
14 kDa
Recommended Dilution:
WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:
Q8N726
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.