The Recombinant CDKN2A/p14ARF Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C311238) against CDKN2A/p14ARF. Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC, IF and IP applications. It has been validated by WB analysis of HeLa, IHC analysis of Human lung squamous carcinoma, IF analysis of HeLa and IP analysis of HeLa cells extracts. The target is localized to the mitochondrion, nucleus.
Product Name:
Recombinant CDKN2A/p14ARF Monoclonal Antibody
SKU:
AGEL6543
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
CDKN, CDKN2, CDKN2A, MLM
Reactivity:
Human
Immunogen:
Recombinant human CDKN2A/p14ARF fragment
Applications:
WBIHCIFIP
Clonality:
Recombinant Monoclonal
Clone No:
C311238
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CDKN2A/p14ARF
Conjugation:
Unconjugated
Observed MW:
14 kDa
Calculated MW:
14 kDa
Recommended Dilution:
WB 1:500-2000; IHC 1:200-1000; IF 1:50; IP 1:50-100
UniProt:
Q8N726
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.