The Recombinant COX IV Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111396) against COX IV. Cytochrome c oxidase IV (COX4) is component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. COX4 is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF, FC and IP applications. It has been validated by WB analysis of Mouse heart, Rat heart and IF analysis of HepG2. The target is localized to the mitochondrion.
Product Name:
Recombinant COX IV Monoclonal Antibody
SKU:
AGEL6701
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
AL024441, COX, COX 4, COX IV, COX IV 1, COX IV-1, COX4, COX4-1, COX41, Cox4a, COX4B, COX4I, COX4I1, COX4I2, COX4L2, COXIV, COXIV-1, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform, Cytochrome c oxidase subunit 4 isoform 1, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, Cytochrome C Oxidase subunit IV, Cytochrome c oxidase subunit IV isoform 1, Cytochrome c oxidase subunit IV isoform 2 (lung), Cytochrome c oxydase subunit 4, dJ857M17.2, m, MGC105470, MGC72016, mitochondrial
Reactivity:
Human, Mouse, Rat
Immunogen:
A synthetic peptide of human COX IV
Applications:
WBIHC-PICC/IFFCIP
Clonality:
Recombinant Monoclonal
Clone No:
C111396
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
COX IV
Conjugation:
Unconjugated
Observed MW:
17 kDa
Calculated MW:
20 kDa
Recommended Dilution:
WB 1:1000; IHC-P 1:200-500; ICC/IF 1:500-1000; IP 1:20; FCM 1:20
UniProt:
P13073
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.