The Recombinant ELNE Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C370919) against ELNE. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Bovine samples.
This antibody is suitable for WB, IF, IP and ELISA applications. It has been validated by WB analysis of THP-1. The target is localized to the cytoplasmic vesicle, phagosome, Localized in phagolysosomes following ingestion of E.coli by neutrophils.