Description
Recombinant EpCAM Monoclonal Antibody
The Recombinant EpCAM Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C113341) against EpCAM. Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of MCF7, HCT116, T47D, Hela and IF analysis of Human breast cancer, MCF-7. The target is localized to the cytoplasm.
| Product Name: | Recombinant EpCAM Monoclonal Antibody |
| SKU: | AGEL8646 |
| Size: | 50 µL, 100 µL |
| Antibody Type: | Recombinant Monoclonal Antibody |
| Synonyms: | 17 1A, 323/A3, 35-KD glycoprotein, Adenocarcinoma associated antigen, Adenocarcinoma-associated antigen, Antigen identified by monoclonal AUA1, AUA1, CD326, CD326 antigen, Cell surface glycoprotein Trop 1, Cell surface glycoprotein Trop 2, Cell surface glycoprotein Trop-1, chromosome 4, CO 17A, CO17, CO17 1A, CO17A, DIAR5, EGP, EGP 2, EGP2, EGP314, EGP40, Ep CAM, Ep-CAM, EPCAM, EpCAM1, Epithelial cell adhesion molecule, Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD), Epithelial cell surface antigen, Epithelial cellular adhesion molecule, Epithelial glycoprotein, Epithelial glycoprotein 1, Epithelial glycoprotein 314, ESA, GA733 1, GA733 2, GA733-2, gastrointestinal tumor-associated antigen 2, gp4, hEGP 2, hEGP314, HNPCC8, Human epithelial glycoprotein 2, KS 1/4 antigen, KS1/4, KSA, Ly74, Lymphocyte antigen 74, M1S 1, M1S2, M4S1, Major gastrointestinal tumor associated protein GA733 2, Major gastrointestinal tumor-associated protein GA733-2, mEGP314, Membrane component, Membrane component chromosome 4 surface marker (35kD glycoprotein), MIC18, MK 1, Protein 289A, surface marker, surface marker 1, TACD1, TACSTD1, TROP1, Tumor associated calcium signal transducer 1, Tumor associated calcium signal transducer 2 precursor, Tumor-associated calcium signal transducer 1 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant protein of human EpCAM |
| Applications: | WBIHC-PIF |
| Clonality: | Recombinant Monoclonal |
| Clone No: | C113341 |
| Host: | Rabbit |
| Isotype: | Rabbit IgG |
| Target: | EpCAM |
| Conjugation: | Unconjugated |
| Observed MW: | 40 kDa |
| Calculated MW: | 35 kDa |
| Recommended Dilution: | WB 1:500-1000; IHC 1:50-100; IF 1:20-100 |
| UniProt: | P16422 |
| Purification: | Affinity purification |
| Concentration: | 0.3 mg/mL |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein. |
| Storage: | Store at -20°C valid for 12 months. Avoid freeze / thaw cycles. |
