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Key Features

Recombinant GCLC Monoclonal Antibody (AGEL5735)

Datasheet MSDS
SKU AGEL5735
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C170417
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant GCLC Monoclonal Antibody

The Recombinant GCLC Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C170417) against GCLC. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IF, IP and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the cytoplasm.

Product Name:Recombinant GCLC Monoclonal Antibody
SKU:AGEL5735
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:EC 6.3.2.2, Gamma ECS, Gamma glutamylcysteine synthetase, Gamma-ECS, Gamma-glutamylcysteine synthetase, GCL, GCLC, GCS, GCS heavy chain, GCSc-γ, GLCL, GLCLC, Glutamate cysteine ligase catalytic subunit, Glutamate--cysteine ligase catalytic subunit, GSH, GSH1
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant Human GCLC protein
Applications:WBIFIPELISA
Clonality:Recombinant Monoclonal
Clone No:C170417
Host:Rabbit
Isotype:Rabbit IgG
Target:GCLC
Conjugation:Unconjugated
Observed MW:73 kDa
Calculated MW:73 kDa
Recommended Dilution:WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200
UniProt:P48506
Purification:Protein A
Concentration:0.2 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Product ImageWestern Blot with Recombinant GCLC Monoclonal Antibody at dilution of 1:1000 dilution. Lane A: Hela cell lysate. Observed-MW:73 kDa Calculated-MW:73 kDa
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